Pathway Analysis Applications for Systems Biology

Meaningful modelling of biomolecular pathways and networks requires access to accurate datasets of biomolecular interactions and their biological context. To achieve the required accuracy, pathway databases such as Metacore and Ingenuity Pathway Analysis (IPA) rely on hundreds of curators who manually review the journal and patent literature, and employ specialised software to populate the interactions databases. The Metacore database, for example, provides semantically consistent descriptions of protein-protein, protein-DNA and protein-RNA signalling, protein-ligand interactions, protein complexes and the reactions of endogenous and xenobiotic metabolism in over 1.3 million manually curated interactions (as of April 2014).

Access to Metacore and Metadrug

  • QFAB is a Centre of Excellence. Researchers at the University of Queensland, Queensland University of Technology, Griffith University and Macquarie University can request a login.
  • Please contact QFAB to request a login or to discuss your requirements

 

Access to IPA